Study of gene expression with molecular biological methods during mammalian embryo preimplantation development
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چکیده
منابع مشابه
Molecular Basis of Differential Gene Expression in Themouse Preimplantation Embryo
Preimplantation development of the mammalian embryo consists of stages that include formation of the <span style="font-variant: normal; font-style: normal; font-family: ArialM...
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Background: Mammalian preimplantation development is a complex process involving dramatic changes in the transcriptional architecture. However, it is still unclear about the crucial transcriptional network and key hub genes that regulate the proceeding of preimplantation embryos. Materials and Methods: Through single-cell RNAsequencing (RNA-seq) of both human and mouse preimplantation embryos, ...
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Background: Chromosome abnormalities are associated with poor morphology and development in human preimplantation embryos, all together lead to poor outcomes. This study aimed to explore altered expression of DNA damage pathways in “poor morphological and development embryos with sever aneuploidies”. Materials and Methods: Surplus day-4 embryos of PGD cases were pooled in two groups: Poor progn...
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Background: While mammalian embryos can adapt to their environments, their sensitivity overshadows their adaptability in suboptimal in vitro conditions. Therefore, the environment in which the gametes are fertilized or to which the embryo is exposed can greatly affect the quality of the embryo and consequently its implantation potential. Objectives:</stro...
متن کاملMolecular basis of differential gene expression in the mouse preimplantation embryo
Preimplantation development of the mammalian embryo consists of stages that include formation of the zygote, blastocyst formation and implantation of the embryo into the uterus. Depending on the animal, first few cleavages of the early embryo is fully supported by translation of maternal transcripts and use of maternal proteins. After this period, the preimplantation embryo starts to transcribe...
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